Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice
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چکیده
منابع مشابه
Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice
To evaluate RNA oxidation in the early stage of diabetic nephropathy, we applied an accurate method based on isotope dilution high-performance liquid chromatography-triple quadruple mass spectrometry to analyze the oxidatively generated guanine nucleosides in renal tissue and urine from db/db mice of different ages. We further investigated the relationship between these oxidative stress markers...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2017
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2017/2353729